CXCR3 Mouse Monoclonal Antibody [Clone ID: 1C6]

Specifications

Product Data
Clone Name	1C6
Recommend Dilution	WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	A 37aa-synthetic peptide corresponding to the N-terminus of human CXCR3 conjugated to KLH.
Formulation	This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification	The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	~41 kDa
Gene Name	C-X-C motif chemokine receptor 3
Database Link	NP_001136269 Entrez Gene 12766 MouseEntrez Gene 84475 RatEntrez Gene 2833 Human UniProt ID P49682
Background	Chemokine receptors are seven-transmembrane domain G-protein coupled receptors that mediate the biological activities of chemokines. Most of these receptors exhibit promiscuous binding properties whereby several different chemokines signal through the same receptor. They are named according to the chemokine subfamily they bind. There are currently six CXC-specific receptors designated CXCR1 to CXCR6. This antibody recognizes surface expressed CXCR3, as judged by staining of CXCR3 transfected cells, but not untransfected cells. The antibody also stained human T cells and T cell clones that had been activated in vitro with PHA or anti-CD3. However, the anti-CXCR3 antibody did not react with neutrophils. The CXCR3 receptor is also known as the IP-10 receptor and the Mig receptor.
Synonyms	CD182; CD183; CKR-L2; CMKAR3; GPR9; IP10-R; Mig-R; MigR
Reference Data
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Chemokine signaling pathway, Cytokine-cytokine receptor interaction

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.