ICAM1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein encoding aa 253-367 of human CD54.
Formulation	This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification	The Rabbit IgG is purified by Epitope Affinity Purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	85~110 kDa
Gene Name	intercellular adhesion molecule 1
Database Link	NP_000192 Entrez Gene 3383 Human UniProt ID P05362
Background	The CD54 antigen (ICAM-1) is an integral membrane glycoprotein of 85-110kDa with seven potential N-linked glycosylation sites. The cell surface glycoprotein is typically expressed on endothelial cells and the cells of the immune system, such as monocytes. It binds to integrins of type CD11a/CD18, or CD11b/CD18. Expression of the CD54 glycoprotein can be induced or upregulated on many cells types including B and T lymphocytes, thymocytes, fibroblasts, keratinocytes and epithelial cells. The CD54 antigen is important in mediating immune and inflammatory responses.
Synonyms	BB2; CD54; P3.58
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways	Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Natural killer cell mediated cytotoxicity, Viral myocarditis

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.