TMEM49 (VMP1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Human plasma solution, HepG2 cell, 293T cell, Hela cell lysates IHC: 50-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm and Nucleus
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human VMP1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	46 kDa
Gene Name	vacuole membrane protein 1
Database Link	NP_112200 Entrez Gene 81671 Human UniProt ID Q96GC9
Background	VMP1 (Vacuole membrane protein 1), is a 406 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum-golgi intermediate compartment membrane. Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis. Plays a role in the initial stages of the autophagic process through its interaction with BECN1 (By similarity). Involved in cell-cell adhesion.
Synonyms	EPG3; TANGO5; TMEM49
Reference Data
Protein Families	Transmembrane

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