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RANK (TNFRSF11A) Rabbit Polyclonal Antibody
CAT＃: TA351580S
Rabbit Polyclonal Anti-TNFRSF11A Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 4,840.00
Specifications
| Product Data | |
| Applications | WB |
| Recommend Dilution | WB: 500-2000 WB positive control: Mouse kidney tissue, Mouse small intestines tissue lysates |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human TNFRSF11A |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 66 kDa |
| Gene Name | tumor necrosis factor receptor superfamily member 11a |
| Database Link | |
| Background | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. |
| Synonyms | CD265; FEO; LOH18CR1; ODFR; OFE; OPTB7; OSTS; PDB2; RANK; TRANCER |
| Reference Data | |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction |
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