LASS6 (CERS6) Rabbit Polyclonal Antibody
CAT#: TA351345
Rabbit Polyclonal Anti-CERS6 Antibody
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CNY 1,999.00
CNY 3,280.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
Specifications
Product Data | |
Applications | IHC |
Recommend Dilution | IHC: 50-200 Positive control: Human ovarian cancer Predicted cell location: Nucleus |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human CERS6 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | ceramide synthase 6 |
Database Link | |
Background | The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they all are involved in sphingolipid synthesis. LASS6 is a widely expressed 384 amino acid endoplasmic reticulum, multi-pass membrane protein. On the luminal side of the endoplasmic reticulum membrane, the N-terminal asparagine residue is glycosylated. In cells deficient for CLN9, LASS6 corrects growth and apoptosis, and increases the levels of short ceramide species, such as C14:0- and C16:0-ceramides. |
Synonyms | CERS5; LASS6 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
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