Bile salt activated lipase (CEL) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Mouse Pancreas tissue lysate IHC: 50-200 Positive control: Human gastric cancer Predicted cell location: secreted
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human CEL
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	79 kDa
Gene Name	carboxyl ester lipase
Database Link	NP_001798 Entrez Gene 12613 MouseEntrez Gene 1056 Human
Background	The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted.
Synonyms	BAL; BSDL; BSSL; CEase; CELL; FAP; FAPP; LIPA; MODY8
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Glycerolipid metabolism, Metabolic pathways, Steroid biosynthesis

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