AATF Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 200-1000 WB positive control: Mouse heart tissue and 231 cells
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human AATF
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	63 kDa
Gene Name	apoptosis antagonizing transcription factor
Database Link	NP_036270 Entrez Gene 56321 MouseEntrez Gene 114512 RatEntrez Gene 26574 Human UniProt ID Q9NY61
Background	The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.
Synonyms	BFR2; CHE-1; CHE1; DED
Reference Data
Protein Families	Druggable Genome, Stem cell - Pluripotency, Transcription Factors

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