KMT2D Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human brain Predicted cell location: Nucleus
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human KMT2D
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	lysine methyltransferase 2D
Database Link	NP_003473 Entrez Gene 8085 Human UniProt ID O14686
Background	The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome.
Synonyms	AAD10; ALR; CAGL114; KABUK1; KMS; MLL2; MLL4; TNRC21
Reference Data
Protein Families	Druggable Genome

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