TRIM21 Rabbit Polyclonal Antibody
CAT#: TA350447S
Rabbit Polyclonal Anti-TRIM21 rabbit polyclonal antibody
Size: 100 ul
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Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB: 1000-5000 WB positive control: Lovo, A549 and hela cells |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Fusion protein of human TRIM21 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 54 kDa |
Gene Name | tripartite motif containing 21 |
Database Link | |
Background | This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. |
Synonyms | RNF81; Ro; RO52; SSA; SSA1 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Systemic lupus erythematosus |
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