PNMT Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 500-2000 WB positive control: K562 cells and human liver cancer tissue, Jurkat and A549 cells
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human PNMT
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	31 kDa
Gene Name	phenylethanolamine N-methyltransferase
Database Link	NP_002677 Entrez Gene 18948 MouseEntrez Gene 24661 RatEntrez Gene 5409 Human UniProt ID P11086
Background	The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene.
Synonyms	PENT; PNMTase
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Metabolic pathways, Tyrosine metabolism

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