DDIT4 Rabbit Polyclonal Antibody

CAT#: TA349879S

Rabbit Polyclonal Anti-DDIT4 Antibody

Size: 25 ul 100 ul



Need it in bulk or conjugated?
Get a free quote

CNY 800.00

CNY 1,280.00


货期*
2周

规格
    • 25 ul

Product images

经常一起买 (3)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
CNY 1,430.00


Recombinant protein of human DNA-damage-inducible transcript 4 (DDIT4), 20 µg
    • 20 ug

CNY 2,900.00
CNY 6,650.00


Transient overexpression lysate of DNA-damage-inducible transcript 4 (DDIT4)
    • 100 ug

CNY 3,080.00

Specifications

Product Data
Applications IHC
Recommend Dilution IHC: 50-200
Positive control: Human liver cancer
Predicted cell location: Cytoplasm
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Fusion protein of human DDIT4
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name DNA damage inducible transcript 4
Background REDD-1, also designated DNA-damage-inducible transcript 4, dig2 or RTP801, is thought to function in the regulation of reactive oxygen species (ROS). REDD-1 expression has also been linked to apoptosis, Ab toxicity and the pathogenesis of ischemic diseases. As an HIF-1-responsive gene, REDD-1 exhibits strong hypoxia-dependent upregulation in ischemic cells of neuronal origin. In response to stress due to DNA damage and glucocorticoid treatment, REDD-1 is upregulated at the transcriptional level. REDD-1 negatively regulates the mammalian target of Rapamycin (mTOR), a serine/threonine kinase often referred to as FRAP. It is crucial in the coupling of extra- and intracellular cues to FRAP regulation. The absence of REDD-1 is associated with the development of retinopathy, a major cause of blindness.
Synonyms Dig2; REDD-1; REDD1
Reference Data
Protein Pathways mTOR signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Customer Reviews 
Loading...