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FBXW7 Rabbit Polyclonal Antibody
CAT＃: TA349784S
Rabbit Polyclonal Anti-FBXW7 Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 4,840.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 100-300 Positive control: Human cervical cancer Predicted cell location: Cytoplasm or Nucleus |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human FBXW7 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | F-box and WD repeat domain containing 7 |
| Database Link | |
| Background | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class; in addition to an F-box, this protein contains 7 tandem WD40 repeats. |
| Synonyms | AGO; CDC4; FBW6; FBW7; FBX30; FBXO30; FBXW6; hAgo; hCdc4; SEL-10; SEL10 |
| Reference Data | |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Ubiquitin mediated proteolysis |
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