United States
Germany
Japan
United Kingdom
China
PIM2 Rabbit Polyclonal Antibody
CAT＃: TA349603S
Rabbit Polyclonal Anti-PIM2 Antibody
Size: 100 ul
Need it in bulk or conjugated?
Get a free quote
CNY 800.00
CNY 1,280.00
Product images
CNY 300.00
CNY 1,430.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 50-200 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human PIM2 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | Pim-2 proto-oncogene, serine/threonine kinase |
| Database Link | |
| Background | This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival. Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression, the regulation of cap-dependent protein translation and through survival signaling by phosphorylation of a pro-apoptotic protein, BAD. Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase transcriptional activity. |
| Synonyms | Pim-2h |
| Reference Data | |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Acute myeloid leukemia |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
| 抗体相关资料 |
