GEF H1 (ARHGEF2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human breast cancer Predicted cell location: Nucleus
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human ARHGEF2
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	Rho/Rac guanine nucleotide exchange factor 2
Database Link	NP_004714 Entrez Gene 16800 MouseEntrez Gene 310635 RatEntrez Gene 9181 Human UniProt ID Q92974
Background	Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms	GEF; GEF-H1; GEFH1; LFP40; P40
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Pathogenic Escherichia coli infection

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