SFRS3 (SRSF3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	SRSF3 antibody was raised against a 19 amino acid peptide near the center of human SRSF3.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	SRSF3 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 18 kDa; Observed: 19 kDa
Gene Name	serine/arginine-rich splicing factor 3
Database Link	NP_003008 Entrez Gene 6428 Human UniProt ID P84103
Background	SRSF3, a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors which constitute part of the spliceosome, may be involved in RNA processing in relation with cellular proliferation and/or maturation (1,2). Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins (3). The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation (3,4).
Synonyms	EFC; RFX
Reference Data

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