IFIT1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	IFIT1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human IFIT1.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	IFIT1 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 53 kDa; Observed: 53 kDa
Gene Name	interferon induced protein with tetratricopeptide repeats 1
Database Link	NP_001539 Entrez Gene 15957 MouseEntrez Gene 56824 RatEntrez Gene 3434 Human UniProt ID P09914
Background	The interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) protein is a member of a family of tetratricopeptide repeat-containing proteins whose transcription is upregulated by interferons, virus infection, and molecular patterns such as dsRNA or lipopolysaccharides (1,2). These proteins have been suggested to induce anti-viral cellular activities in response to infection (2). Together with the interferon-induced transmembrane protein 1 (IFITM1), IFIT1 inhibits the replication of the Hepatitis C virus, suggesting that it may be useful in the development of therapeutic treatments (3).
Synonyms	C56; G10P1; IFI-56; IFI-56K; IFI56; IFIT-1; IFNAI1; ISG56; P56; RNM561
Reference Data

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