RAN Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-RAN Antibody: A synthesized peptide derived from human RAN
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	26 kDa
Gene Name	RAN, member RAS oncogene family
Database Link	NP_006316 Entrez Gene 19384 MouseEntrez Gene 84509 RatEntrez Gene 5901 Human UniProt ID P62826
Background	GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules.
Synonyms	ARA24; Gsp1; TC4
Note	RAN Antibody detects endogenous levels of total RAN
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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