CD147 (BSG) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-CD147 Antibody: A synthesized peptide derived from human CD147
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	48,36 kDa
Gene Name	basigin (Ok blood group)
Database Link	NP_940993 Entrez Gene 12215 MouseEntrez Gene 25246 RatEntrez Gene 682 Human UniProt ID P35613
Background	BSG Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). May target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes. Enriched on the surface of tumor cells. Up-regulated in gliomas. Its expression levels correlate with malignant potential of the tumor.
Synonyms	5F7; CD147; EMMPRIN; OK; TCSF
Note	CD147 Antibody detects endogenous levels of CD147
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Transmembrane

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