PTPN22 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:3000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-PTPN22 Antibody: A synthesized peptide derived from human PTPN22
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Affinity-chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	91 kDa
Gene Name	protein tyrosine phosphatase, non-receptor type 22
Database Link	NP_057051 Entrez Gene 19260 MouseEntrez Gene 295338 RatEntrez Gene 26191 Human UniProt ID Q9Y2R2
Background	PTPN22 Seems to act on Cbl. May play a role in regulating the function of Cbl and its associated protein kinases. Acts as negative regulator of T cell receptor (TCR) signaling. Dephosphorylates and inactivates the SRC family kinases. Belongs to the protein-tyrosine phosphatase family.
Synonyms	LYP; LYP1; LYP2; PEP; PTPN8
Note	PTPN22 antibody detects endogenous levels of total PTPN22
Reference Data
Protein Families	Druggable Genome, Phosphatase

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