RANKL (TNFSF11) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:3000
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-TNFSF11 Antibody: A synthesized peptide derived from human TNFSF11
Formulation	PBS, pH 7.4,50% glycerol.
Concentration	lot specific
Purification	Affinity-chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	40 kDa
Gene Name	tumor necrosis factor superfamily member 11
Database Link	NP_003692 Entrez Gene 21943 MouseEntrez Gene 8600 Human UniProt ID O14788
Background	TNFSF11 Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.
Synonyms	CD254; hRANKL2; ODF; OPGL; OPTB2; RANKL; sOdf; TRANCE
Note	TNFSF11 antibody detects endogenous levels of total TNFSF11
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Cytokine-cytokine receptor interaction

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