NYREN18 (NUB1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:3000
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-NYREN18 Antibody: A synthesized peptide derived from human NYREN18
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Affinity-chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	70 kDa
Gene Name	negative regulator of ubiquitin-like proteins 1
Database Link	NP_057202 Entrez Gene 53312 MouseEntrez Gene 51667 Human UniProt ID Q9Y5A7
Background	NYREN18 Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8 and its conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2. Induced by beta and gamma interferons. Directly interacts with NEDD8 and PSMD4/S5a, a member of the regulatory subunit of the 26S proteasome.
Synonyms	BS4; NUB1L; NYREN18
Note	NYREN18 antibody detects endogenous levels of total NYREN18
Reference Data
Protein Families	Druggable Genome

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