SAE1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:3000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-AOS1 Antibody: A synthesized peptide derived from human AOS1
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Affinity-chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	38 kDa
Gene Name	SUMO1 activating enzyme subunit 1
Database Link	NP_005491 Entrez Gene 56459 MouseEntrez Gene 308384 RatEntrez Gene 10055 Human UniProt ID Q9UBE0
Background	UBLE1A The dimeric enzyme acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins and formation of a thioester with a conserved cysteine residue on SAE2. Belongs to the ubiquitin-activating E1 family. Heterodimer of SAE1 and SAE2. The complex binds SUMO proteins via SAE2.
Synonyms	AOS1; HSPC140; SUA1; UBLE1A
Note	AOS1 antibody detects endogenous levels of total AOS1
Reference Data
Protein Pathways	Ubiquitin mediated proteolysis

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