Ku80 (XRCC5) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:3000
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-Ku80 Antibody: A synthesized peptide derived from human Ku80
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Affinity-chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	70 kDa,82 kDa
Gene Name	X-ray repair complementing defective repair in Chinese hamster cells 5
Database Link	NP_066964 Entrez Gene 7520 Human UniProt ID P13010
Background	Ku80 the 80-kilodalton subunit of the Ku complex, also known as ATP-dependant DNA helicase II. A single stranded DNA-dependent ATP-dependent helicase. It functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events.
Synonyms	KARP-1; KARP1; KU80; Ku86; KUB2; NFIV
Note	Ku80 antibody detects endogenous levels of total Ku80
Reference Data
Protein Families	Druggable Genome, Stem cell - Pluripotency
Protein Pathways	Non-homologous end-joining

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