Caveolin 1 (CAV1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:3000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-Caveolin-1 Antibody: A synthesized peptide derived from human Caveolin-1
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Affinity-chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	25 kDa
Gene Name	caveolin 1
Database Link	NP_001744 Entrez Gene 12389 MouseEntrez Gene 25404 RatEntrez Gene 857 Human UniProt ID Q03135
Background	caveolin-1 May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Involved in the costimulatory signal essential for T-cell receptor (TCR)- mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3- dependent manner. Belongs to the caveolin family. Homooligomer. Interacts with GLIPR2, NOSTRIN, SNAP25 and syntaxin. Interacts with rotavirus A NSP4.
Synonyms	BSCL3; CGL3; LCCNS; MSTP085; PPH3; VIP21
Note	Caveolin-1 antibody detects endogenous levels of total Caveolin-1
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Focal adhesion, Viral myocarditis

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