PPAR gamma (PPARG) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	ELISA (1:1,000); Western blotting (1:2,000); ChIP (1ug/ChIP)
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-PPARG antibody: human PPARG (peroxisome proliferator-activated receptor gamma), using a KLH-conjugated synthetic peptide containing a sequence from the central part of the protein.
Concentration	lot specific
Purification	Affinity purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	peroxisome proliferator activated receptor gamma
Database Link	NP_056953 Entrez Gene 19016 MouseEntrez Gene 5468 Human UniProt ID P37231
Background	PPARG (UniProtKB/Swiss-Prot entry P37231) is a nuclear hormone receptor which binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Like many other nuclear hormone receptors, PPARG forms a heterodimer with the retinoid X receptor (RXR) leading to transcriptional regulation of various genes including acyl-CoA oxidase and cytochrome P450 A6. PPARG has been implicated in adipocyte differentiation and glucose homeostasis and in various diseases such as obesity, diabetes, atherosclerosis and cancer.
Synonyms	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARgamma
Reference Data
Protein Families	Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
Protein Pathways	Huntington's disease, Pathways in cancer, PPAR signaling pathway, Thyroid cancer

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