MBD3 Rabbit Polyclonal Antibody
CNY 4,323.00
货期*
5周
规格
经常一起买 (1)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Applications | ELISA, WB |
Recommend Dilution | ELISA (1:100 ?? 1:500); Western blotting (1:2,000) |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | The immunogen for anti-MBD3 antibody: human MBD3 (Methyl-CpG-binding domain protein 3), using three different KLH-conjugated synthetic peptides. |
Concentration | lot specific |
Purification | Whole antiserum from rabbit containing 0.05% azide. |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | methyl-CpG binding domain protein 3 |
Database Link | |
Background | MBD3 (UniProtKB/Swiss-Prot entry O95983) is a transcriptional repressor which plays a role in gene silencing. Surprisingly, MBD3 does not seem to bind methylated DNA by itself, but acts by the recruitment of histone deacetylases and DNA methyltransferases. MBD3 also forms a heterodimer with MBD2 and is part of the NuRD and the MeCP1 complex. Further, MBD3 interacts with HDAC1, MTA2, DNMT1, p66-alpha and p66-beta. |
Synonyms | MBD3 |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
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