UHRF1 Mouse Monoclonal Antibody [Clone ID: 1H9-D3-E11]
CAT#: TA347069
Mouse Monoclonal UHRF1 (N-terminus) Antibody
Size: 20 ul
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CNY 2,700.00
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Specifications
Product Data | |
Clone Name | 1H9-D3-E11 |
Applications | WB |
Recommend Dilution | WB: 1:1000 |
Reactivity | Human, Mouse |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | The immunogen for UHRF1 antibody: purified recombinant human UHRF1 protein fragments expressed in E.coil. |
Formulation | Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol |
Purification | Affinity purified |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 90 kDa |
Gene Name | ubiquitin like with PHD and ring finger domains 1 |
Database Link | |
Background | This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene. |
Synonyms | hNP95; hUHRF1; huNp95; ICBP90; Np95; RNF106 |
Note | Detects ~ 38kDa. |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
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