NBL1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-NBL1 antibody: synthetic peptide directed towards the middle region of human NBL1. Synthetic peptide located within the following region: GLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	18 kDa
Gene Name	neuroblastoma 1, DAN family BMP antagonist
Database Link	NP_005371 Entrez Gene 4681 Human UniProt ID P41271
Background	This gene product isThe founding member ofThe evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resemblingThe CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules.These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventingThem from interacting withTheir receptors.They may thus play an important role during growth and development. Alternatively spliced transcript variants have been identified forThis gene. Read-through transcripts betweenThis locus andThe upstream mitochondrial inner membrane organizing system 1 gene (GeneID 440574) have been observed. [provided by RefSeq, May 2013]
Synonyms	D1S1733E; DAN; DAND1; NB; NO3
Note	Immunogen Sequence Homology: Dog: 100%; Pig: 100%; Horse: 100%; Human: 100%; Bovine: 100%; Mouse: 93%; Rabbit: 93%; Rat: 86%
Reference Data
Protein Families	Secreted Protein

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