COQ2 Rabbit Polyclonal Antibody
CNY 5,250.00
货期*
6周
规格
Cited in 2 publications. |
经常一起买 (1)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | The immunogen for anti-COQ2 antibody: synthetic peptide directed towards the middle region of human COQ2. Synthetic peptide located within the following region: FSGVMWTLIYDTIYAHQDKRDDVLIGLKSTALRFGENTKPWLSGFSVAML |
Formulation | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 42 kDa |
Gene Name | coenzyme Q2, polyprenyltransferase |
Database Link | |
Background | This gene encodes an enzyme that functions inThe final steps inThe biosynthesis of CoQ (ubiquinone), a redox carrier inThe mitochondrial respiratory chain and a lipid-soluble antioxidant.This enzyme, which is part ofThe coenzyme Q10 pathway, catalyzesThe prenylation of parahydroxybenzoate with an all-trans polyprenyl group. Mutations inThis gene cause coenzyme Q10 deficiency, a mitochondrial encephalomyopathy, and also COQ2 nephropathy, an inherited form of mitochondriopathy with primary renal involvement. [provided by RefSeq, Oct 2009] |
Synonyms | CL640; COQ10D1; MSA1 |
Note | Immunogen Sequence Homology: Human: 100%; Dog: 93%; Rabbit: 93%; Yeast: 91%; Pig: 86%; Rat: 86%; Mouse: 86%; Zebrafish: 86%; Goat: 79%; Horse: 79% |
Reference Data | |
Protein Families | Transmembrane |
Protein Pathways | Ubiquinone and other terpenoid-quinone biosynthesis |
Citations (2)
The use of this Antibodies has been cited in the following citations: |
---|
The Q-junction and the inflammatory response are critical pathological and therapeutic factors in CoQ deficiency
,null,
Redox Biology
,PubMed ID 35863266
[COQ2]
|
β-RA reduces DMQ/CoQ ratio and rescues the encephalopathic phenotype in Coq9 R239X mice
,Hidalgo-Gutiérrez, A;Barriocanal-Casado, E;Bakkali, M;Díaz-Casado, ME;Sánchez-Maldonado, L;Romero, M;Sayed, RK;Prehn, C;Escames, G;Duarte, J;Acuña-Castroviejo, D;López, LC;,
EMBO Mol Med
,PubMed ID 30482867
[COQ2]
|
Documents
Product Manuals |
FAQs |
SDS |
Resources
抗体相关资料 |
Customer
Reviews
Loading...