MCM8 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB, IHC
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-MCM8 antibody: synthetic peptide directed towards the C terminal of human MCM8. Synthetic peptide located within the following region: IRLTEARARLELREEATKEDAEDIVEIMKYSMLGTYSDEFGNLDFERSQH
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. Note that this product is shipped as lyophilized powder to China customers.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	94 kDa
Gene Name	minichromosome maintenance 8 homologous recombination repair factor
Database Link	NP_115874 Entrez Gene 84515 Human UniProt ID Q9UJA3
Background	The protein encoded byThis gene is one ofThe highly conserved mini-chromosome maintenance proteins (MCM) that are essential forThe initiation of eukaryotic genome replication.The hexameric protein complex formed byThe mini-chromosome maintenance proteins is a key component ofThe pre-replication complex and may be involved inThe formation of replication forks and inThe recruitment of other DNA replication related proteins.This protein containsThe central domain that is conserved amongThe mini-chromosome maintenance proteins.The encoded protein may interact with other mini-chromosome maintenance proteins and play a role in DNA replication.This gene may be associated with length of reproductive lifespan and menopause. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2013]
Synonyms	C20orf154; dJ967N21.5; POF10
Note	Immunogen Sequence Homology: Pig: 100%; Rat: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Bovine: 100%; Rabbit: 100%; Guinea pig: 100%; Dog: 93%; Zebrafish: 86%
Reference Data
Protein Families	Transcription Factors

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