Fibronectin (FN1) Mouse Monoclonal Antibody [Clone ID: 2F4]

Specifications

Product Data
Clone Name	2F4
Applications	ELISA, FC, ICC/IF, IHC, WB
Recommend Dilution	Flow Cytometry: 1:200 - 1:400, Immunohistochemistry: 1:200 - 11:1000, Immunohistochemistry-Paraffin: 1:200 - 1:1000, Western Blot: 1:500 - 1:1000, ELISA: 1:10000, Immunocytochemistry/ Immunofluorescence: 1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human Fibronectin expressed in E. coli. [UniProt# P02751]
Formulation	Preservative: 0.05% Sodium Azide. Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Concentration	lot specific
Purification	Ascites
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	262.6 kDa
Gene Name	fibronectin 1
Database Link	NP_997639 Entrez Gene 2335 Human UniProt ID P02751
Background	This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined.
Synonyms	CIG; ED-B; FINC; FN; FNZ; GFND; GFND2; LETS; MSF
Note	This Fibronectin (2F4) antibody is useful for Western blot, Immunohistochemistry on paraffin-embedded sections, Flow Cytometry and ELISA.
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways	ECM-receptor interaction, Focal adhesion, Pathways in cancer, Regulation of actin cytoskeleton, Small cell lung cancer

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