Heparin Cofactor II (SERPIND1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB 1:500 - 1:2000
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein of human SERPIND1
Formulation	Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	499
Gene Name	serpin family D member 1
Database Link	NP_000176 Entrez Gene 15160 MouseEntrez Gene 3053 Human UniProt ID P05546
Background	The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in this gene are associated with heparin cofactor II deficiency.
Synonyms	D22S673; HC2; HCF2; HCII; HLS2; LS2; THPH10
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Complement and coagulation cascades

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