PC4 (SUB1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB, IHC
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-PC4 antibody: synthetic peptide directed towards the middle region of human PC4. Synthetic peptide located within the following region: NMFQIGKMRYVSVRDFKGKVLIDIREYWMDPEGEMKPGRKGISLNPEQWS
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	14 kDa
Gene Name	SUB1 homolog, transcriptional regulator
Database Link	NP_006704 Entrez Gene 10923 Human UniProt ID P53999
Background	PC4 (activated RNA polymerase II transcription cofactor 4) is a transcriptional coactivator, possessing the ability to suppress promoter-driven as well as nonspecific transcription via its DNA binding activity. The repressive activity of PC4 on promoter-driven transcription is alleviated by transcription factor TFIIH. TFIIH protects promoters from PC4-mediated repression by relieving the topological constraint imposed by PC4 through the ERCC3 helicase activity.
Synonyms	p14; P15; PC4
Note	Immunogen sequence homology: Bovine:100%; Human:100%; African clawed frog:100%; Western clawed frog:100%; Rat:100%; Chicken:100%; Sumatran orangutan:100%; Zebrafish:100%; Crab-eating macaque:100%; Mouse:100%; Dog:100%; salmon louse:100%; Northern pike:100
Reference Data
Protein Families	Transcription Factors

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