CD13 (ANPEP) Goat Polyclonal Antibody

CAT#: TA329673

Goat Anti-CD13 / ANPEP Polyclonal Antibody



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CNY 5,371.00


货期*
5周

规格
    • 100 ug

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Purified recombinant protein of Homo sapiens alanyl (membrane) aminopeptidase (ANPEP), 20 µg
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Purified recombinant protein of Homo sapiens alanyl (membrane) aminopeptidase (ANPEP), 100 µg
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Specifications

Product Data
Applications WB
Recommend Dilution WB: 0.03-0.1ug/ml
Reactivity Human
Host Goat
Clonality Polyclonal
Immunogen Peptide with sequence C-QLEQFKKDNEET, from the internal region (near C terminus) of the protein sequence according to NP_001141.2
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Concentration lot specific
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name alanyl aminopeptidase, membrane
Background Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. [provided by RefSeq, Jul 2008]
Synonyms APN; CD13; GP150; LAP1; P150; PEPN
Note The observed molecular weight corresponds to the glycosylated form.
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Protease, Transmembrane
Protein Pathways Glutathione metabolism, Hematopoietic cell lineage, Metabolic pathways, Renin-angiotensin system
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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