Kcnh5 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:200-1:2000; IHC: 1:100-1:3000
Reactivity	Human, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Peptide (C)EDPKGSDSENSVTKNPLRK,? corresponding to amino acid residues 842-860 of rat Kv10.2? . Intracellular, C-terminus.
Formulation	Lyophilized. Concentration before lyophilization ~0.8mg/ml (lot dependent, please refer to CoA along with shipment for actual concentration). Buffer before lyophilization: Phosphate buffered saline (PBS), pH 7.4, 1% BSA, 5% sucrose, 0.05% NaN3.
Reconstitution Method	Add 50 ul double distilled water (DDW) to the lyophilized powder.
Purification	Affinity purified on immobilized peptide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	potassium voltage-gated channel subfamily H member 5
Database Link	NP_598294 Entrez Gene 27133 HumanEntrez Gene 171146 Rat UniProt ID Q9EPI9
Background	KV10.2 is a member of the Ether-a-go-go family of voltage-activated potassium channels. The family includes today 8 members: the closely related KV10.1 protein, the KV12 (elk) (elk1, elk2, elk3) and the KV11 (erg) proteins (erg1, erg2, erg3). The eag subfamily current is characterized by outward rectification without inactivation and slow activation kinetics. No specific pharmacological blocker has been described. Tissue distribution of KV10.2 expression in rats is restricted to neuronal tissue with greater expression in the cortex and thalamus. In humans, KV10.2 mRNA was detected in heart and skeletal muscle in addition to brain. The physiological role of KV10.2 is unknown at the moment.
Synonyms	EAG2; H-EAG2; hEAG2; Kv10.2
Reference Data

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