Glra3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:200-1:2000
Reactivity	Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Peptide (C)KNKTEAFALEKFYR, corresponding to amino acid residues 355-368 of rat Glycine Receptor a3. 2nd intracellular loop.
Formulation	Lyophilized. Concentration before lyophilization ~0.8mg/ml (lot dependent, please refer to CoA along with shipment for actual concentration). Buffer before lyophilization: Phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.
Reconstitution Method	Add 50 ul double distilled water (DDW) to the lyophilized powder.
Purification	Affinity purified on immobilized antigen.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	glycine receptor, alpha 3
Database Link	NP_446176 Entrez Gene 114516 Rat
Background	Glycine is a major neurotransmitter in the mammalian central nervous system.The glycine receptor is a ligand gated Cl- channel, mediating synaptic inhibition in the spinal cord, retina and regions of the brain.The glycine receptor is a pentamer consisting of a and Ã? subunits.To date there are four known a-subunit isoforms (a1- a4) encoded by different genes.In humans, two alternative splice variants of the glycine receptor a3 have been described: a3L, and a3K where the a3L splice variant bears an additional segment of 15 amino acids within the long cytoplasmic TM3-4 loop. These variants differ in their desensitization kinetics.
Synonyms	GLRA3
Reference Data

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