Cyclin B1 (CCNB1) Mouse Monoclonal Antibody [Clone ID: V152]

Specifications

Product Data
Clone Name	V152
Applications	WB
Recommend Dilution	WB, IF, IHC
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Hamster Cyclin B1
Formulation	This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. Final antibody concentration is 0.5 mg/ml.
Concentration	lot specific
Purification	The antibody was purified by affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	cyclin B1
Database Link	NP_114172 Entrez Gene 268697 MouseEntrez Gene 891 Human UniProt ID P14635
Background	Cyclin B1 belongs to the cyclin family, Cyclin AB subfamily, and predicted molecular weight 48 kD. Cyclin B1 is expressed ubiquitously in all eukaryotes and the level of cyclin B1 was minimal in G, began to rise in S phase, and is primarily cytoplasmic. Cyclin B1 moves into the nucleus just at the start of mitosis and associates with condensed chromosomes and the mitotic spindle. The level of cyclin B1 peaked at the G/M transition. Cyclin B1 is essential for the control of the cell cycle at the G2/M transition. The V152 monoclonal antibody recognizes human and mouse Cyclin B1 and has been shown to be useful for Western blotting. and immunohistochemistry (paraffin embedded tissue sections) of human and mouse cyclin B1.
Synonyms	CCNB
Reference Data
Protein Families	Druggable Genome, Stem cell - Pluripotency
Protein Pathways	Cell cycle, Oocyte meiosis, p53 signaling pathway, Progesterone-mediated oocyte maturation

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