SSRP1 Mouse Monoclonal Antibody [Clone ID: 3E4]

Specifications

Product Data
Clone Name	3E4
Applications	IF, WB
Recommend Dilution	WB, IP, IF
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant (partial)
Formulation	This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide at 0.5 mg/ml.
Concentration	lot specific
Purification	The antibody was purified by affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	81 kD
Gene Name	structure specific recognition protein 1
Database Link	NP_003137 Entrez Gene 6749 Human UniProt ID Q08945
Background	SSRP1 is a nuclear protein and a component of the FACT complex (facilitates chromatin transcription). The FACT140 complex is composed of the Spt16 and the SSRP1 proteins. This complex interacts with nucleosomes and histone H2A/H2B dimers to promote nucleosome disassembly and allow transcription elongation. This protein interacts with dsDNA. The SSRP1 protein has been shown to be modified by cisplatin and may protect DNA from repair and block DNA replication. The 3E4 monoclonal antibody recognizes human SSRP1 and has been shown to be useful for Western blotting.
Synonyms	FACT; FACT80; T160
Reference Data
Protein Families	Transcription Factors

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