DNA PKcs (PRKDC) Rabbit Polyclonal Antibody

Specifications

Product Data
Recommend Dilution	IHC: 1:50-1:200; IF/ICC: 1:100-1:500
Reactivity	Human
Modifications	Phospho-specific
Host	Rabbit
Clonality	Polyclonal
Immunogen	The antiserum was produced against A synthesized peptide derived from human DNA-PK around the phosphorylation site of Threonine 2647
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	protein kinase, DNA-activated, catalytic polypeptide
Database Link	NP_008835 Entrez Gene 5591 Human UniProt ID P78527
Background	The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q.
Synonyms	DNA-PKcs; DNAPK; DNPK1; HYRC; HYRC1; IMD26; p350; XRCC7
Reference Data
Protein Families	Druggable Genome, Protein Kinase
Protein Pathways	Cell cycle, Non-homologous end-joining

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