Prostate Specific Antigen (KLK3) Mouse Monoclonal Antibody [Clone ID: ER-PR8]

Specifications

Product Data
Clone Name	ER-PR8
Applications	IHC
Recommend Dilution	IHC: 1:50 - 1:200
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Formulation	This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	kallikrein related peptidase 3
Database Link	NP_001639 Entrez Gene 354 Human UniProt ID P07288
Synonyms	APS; hK3; KLK2A1; PSA
Note	PSA is an antigen present in prostate tissue and in the majority of prostate carcinomas. This antibody recognizes primary and metastatic prostatic neoplasms and rarely tumors of nonprostatic origin. These include breast and a minority of salivary gland tumors. The antigen is a 33-34 kD glycoprotein that is restricted to epithelial cells of the prostate. An immunohistochemical study showed more than 95% of prostatic carcinomas stained with anti-PSA. PSA is demonstrable in the cytoplasm of acinar and ductal cells of benign prostate and prostate adenocarcinoma.
Reference Data
Protein Families	Druggable Genome, Protease, Secreted Protein
Protein Pathways	Pathways in cancer, Prostate cancer

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