FANCD2 Rabbit Polyclonal Antibody

CAT#: TA327255

FANCD2 Rabbit Polyclonal Antibody



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CNY 1,999.00

CNY 2,700.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Applications ICC/IF, IP, WB
Recommend Dilution WB 1:500 - 1:2000;IF 1:50- 1:200
Reactivity Human, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant protein of human FANCD2
Formulation Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name Fanconi anemia complementation group D2
Background The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Synonyms FA-D2; FA4; FACD; FAD; FAD2; FANCD
Reference Data
Protein Families Druggable Genome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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