C Reactive Protein (CRP) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ICC/IF, WB
Recommend Dilution	WB 1:500 - 1:2000;IF 1:10 - 1:100
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein of human CRP
Formulation	PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	25 kDa
Gene Name	C-reactive protein, pentraxin-related
Database Link	NP_000558 Entrez Gene 12944 MouseEntrez Gene 25419 RatEntrez Gene 1401 Human UniProt ID P02741
Background	Human c-Reactive protein (CRP) was discovered in serum of patients as a nonantibody precipitin of the C-polysaccharide from pneumococci. During acute infection, the amounts of circulating CPR increases 100-1000 fold . Serum CRP values are routinely measured to detect or monitor many human diseases and minor elevations of C-reactive protein are predictive of cardiovascular events in patients with coronary heart disease . CRP promotes host defense, is an efficient activator of the classical C cascade, and shown to be opsonic .The opsonic and C activation activities are responsible for the nonspecific host defense activities providing protection in the preimmune stage of acute infections. Additionally, IL-1 and IL-6 are known to stimulate CRP biosynthesis .
Synonyms	PTX1
Reference Data
Protein Families	Secreted Protein

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