SUZ12 Rabbit Polyclonal Antibody

CAT#: TA326710

Rabbit Polyclonal SUZ12 Antibody



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CNY 5,808.00


货期*
5周

规格
    • 100 ug

Product images

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Specifications

Product Data
Applications IF, IHC, WB
Recommend Dilution WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen SUZ12 antibody was raised against a 19 amino acid peptide near the center of human SUZ12.
Formulation SUZ12 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration 1 mg/ml
Purification SUZ12 antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size Predicted: 81 kDa; Observed: 96 kDa
Gene Name SUZ12 polycomb repressive complex 2 subunit
Background The Polycomb group (PcG) genes contribute to the maintenance of cell identity, cell cycle regulation and oncogenesis (1). SUZ12 (suppressor of zeste 12) is a 90 - 95 kDa member of the polycomb group of transcriptional regulators (2). It is part of a transcription repression complex termed PRC2 (Polycomb repressive complex 2) that methylates histones in the nucleus, resulting in homeotic (pattern-inducing) gene silencing. It contains one C2H2-type zinc finger region and a C-terminal VEFS-box (3,4). SUZ12 is overexpressed in breast and colon cancer. SUZ12 may be a cause of endometrial stromal tumors (5).
Synonyms CHET9; JJAZ1
Reference Data
Protein Families Transcription Factors
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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