GLIPR1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 - 2 ug/mL, IF: 5 ug/mL
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	GLIPR1 antibody was raised against an 18 amino acid peptide near the center of human GLIPR1.
Formulation	GLIPR1 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	GLIPR1 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 29 kDa; Observed: 24 kDa
Gene Name	GLI pathogenesis related 1
Database Link	NP_006842 Entrez Gene 73690 MouseEntrez Gene 11010 Human UniProt ID P48060
Background	The glioma pathogensis-related protein 1 (GLIPR1) is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family (1). GLIPR1 is a tumor suppressor whose expression is regulated by p53; its increased expression is associated with myelomocytic differentiation in macrophages, whereas decreased expression of this gene through gene methylation is associated with prostate cancer (2). The GLIPR1 gene is part of a p53 target gene cluster that includes GLIPR1L1 and GLIPR1L2, two highly homologous proteins whose expression patterns vary (3).
Synonyms	CRISP7; GLIPR; RTVP1
Reference Data
Protein Families	Transmembrane

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