SAE1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	SAE1 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human SAE1.
Formulation	SAE1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	SAE1 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	SUMO1 activating enzyme subunit 1
Database Link	NP_005491 Entrez Gene 56459 MouseEntrez Gene 308384 RatEntrez Gene 10055 Human UniProt ID Q9UBE0
Background	SAE1 Antibody: Small ubiquitin-like modifiers (SUMOs) are a family of small, related proteins (SUMO-1/2/3/4) that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation, a major regulator of protein function in cellular processes such as nuclear transport, transcriptional regulation, apoptosis and protein stability. This sumoylation is effected by the heterodimeric enzyme SAE1/SAE2 and the SUMO-1-conjugating enzyme Ubch9. The sumoylation pathway mediated by SAE1/SAE2 is distinct from other ubiquitin-like protein (Ubl) pathways.
Synonyms	AOS1; HSPC140; SUA1; UBLE1A
Reference Data
Protein Pathways	Ubiquitin mediated proteolysis

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