Kcna1 Mouse Monoclonal Antibody [Clone ID: S20-78]

Specifications

Product Data
Clone Name	S20-78
Applications	IHC
Recommend Dilution	WB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic peptide amino acids 458-476 (cytoplasmic C-terminus) of rat Kv1.1 (EEDMNNSIAHYRQANIRTG)
Formulation	PBS pH7.4, 50% glycerol
Concentration	lot specific
Purification	Protein G Purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	potassium voltage-gated channel subfamily A member 1
Database Link	NP_775118 Entrez Gene 3736 HumanEntrez Gene 16485 MouseEntrez Gene 24520 Rat UniProt ID P10499
Background	Kv1.1, also known as potassium voltage-gated channel subfamily A member 1, is a shaker related voltage potassium channel that in humans is encoded by the SCNA1 gene . It is strongly expressed in a variety of neurons in adult rodents, and it appears to be involved in regulating neuronal excitability. Specifically it plays a role in several developmental processes including proliferation, migration and cell-cell adhesion . The Isaacs syndrome is a result of an autoimmune reaction against the Kv1.1 ion channel .
Synonyms	AEMK; EA1; HBK1; HUK1; HUKI; Kv1.1; MBK1; MGC126782; MGC138385; MK1; RBK1
Note	~85kDa (major: Mature glycosylation), ~65kDa (minor: immature glycosylation)
Reference Data

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