alpha 2C Adrenergic Receptor (ADRA2C) Mouse Monoclonal Antibody [Clone ID: S330A-80]

Specifications

Product Data
Clone Name	S330A-80
Recommend Dilution	WB: 1:1000
Reactivity	Mouse, Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic peptide amino acids 442- 462 (QDFRRSFKHILFRRRRRGFRQ, cytoplasmic C-terminus) of human Alpha-2C adrenergic receptor
Formulation	PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration	lot specific
Purification	Protein G Purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	adrenoceptor alpha 2C
Database Link	NP_000674 Entrez Gene 11553 MouseEntrez Gene 152 Human UniProt ID P18825
Background	The alpha 2C Adrenergic Receptor controls the release of neurotransmitter from central adrenergic neurons and from sympathetic nerves in the heart. This receptor also plays a role in cognitive and behavioral function. Two variants are produced by alternative splicing. Alpha 2C Adrenergic Receptor has been reported extensively in the brain. Blood, corpus cavermosum, kidney, and heart tissues have also been reported to express the protein.
Synonyms	ADRA2L2; ADRA2RL2; ADRARL2; ALPHA2CAR
Note	Detects 50kDa or larger (possibly due to dimerization). Does not cross-react with other adrenergic receptors.
Reference Data
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Neuroactive ligand-receptor interaction

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