CD45 (PTPRC) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000; IF/ICC: 1:100-1:500
Reactivity	Human, Mouse, Rat
Modifications	Phospho-specific
Host	Rabbit
Clonality	Polyclonal
Immunogen	The antiserum was produced against A synthesized peptide derived from human CD45 around the phosphorylation site of Serine 1007
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	150 kDa
Gene Name	protein tyrosine phosphatase, receptor type C
Database Link	NP_002829 Entrez Gene 19264 MouseEntrez Gene 24699 RatEntrez Gene 5788 Human UniProt ID P08575
Background	The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
Synonyms	B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Phosphatase, Transmembrane
Protein Pathways	Cell adhesion molecules (CAMs), Fc gamma R-mediated phagocytosis, Primary immunodeficiency, T cell receptor signaling pathway

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