DNA Polymerase beta (POLB) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1:500-1:2000; IHC: 1:50-1:200
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The antiserum was produced against a synthesized A synthesized peptide derived from human DNA Polymerase beta.
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	polymerase (DNA) beta
Database Link	NP_002681 Entrez Gene 18970 MouseEntrez Gene 29240 RatEntrez Gene 5423 Human UniProt ID P06746
Background	POLB Repair polymerase. Conducts gap-filling DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5'-deoxyribose-5- phosphate lyase (dRP lyase) activity. Belongs to the DNA polymerase type-X family. Monomer.
Synonyms	MGC125976
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Base excision repair

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