TIMP4 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000; IHC: 1:50-1:200
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The antiserum was produced against A synthesized peptide derived from human TIMP4
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	26 kDa
Gene Name	TIMP metallopeptidase inhibitor 4
Database Link	NP_003247 Entrez Gene 110595 MouseEntrez Gene 680130 RatEntrez Gene 7079 Human UniProt ID Q99727
Background	TIMP4 Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP- 9. Belongs to the protease inhibitor I35 (TIMP) family.
Synonyms	TIMP metallopeptidase inhibitor 4; tissue inhibitor of metalloproteinase 4
Reference Data
Protein Families	Druggable Genome, Secreted Protein

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